Who can take Paxlovid^®

Age

• The CDC recommends treatment for anyone 50 and older
• People who are 65 years of age or older are at the highest risk

Physical Diseases and Conditions

Blood disorders

• Sickle cell disease or thalassemia

Cancer

Cerebrovascular disease

• Stroke

Chronic kidney problems

• People with moderate-to-severe renal impairment will need different doses or dosing schedules of PAXLOVID

Chronic liver problems

• Cirrhosis (or scarring of the liver)
• Non-alcoholic fatty liver disease
• Alcohol-related liver disease
• Autoimmune hepatitis
• PAXLOVID is not recommended for people with severe liver disease

Chronic lung diseases

• Moderate-to-severe asthma
• Bronchiectasis (thickening of the lungs’ airways)
• A chronic lung disease affecting newborns called bronchopulmonary dysplasia
• Chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis
• Damaged or scarred lung tissue known as interstitial lung disease (including idiopathic pulmonary fibrosis)
• Pulmonary embolism (blood clot in the lungs)
• Pulmonary hypertension (high blood pressure in the lungs)

Cystic fibrosis

Diabetes type 1 and type 2

Heart conditions

• Heart failure
• Coronary artery disease (damage or disease in the heart's major blood vessels)
• Cardiomyopathies (heart muscle diseases)
• Possibly high blood pressure (hypertension)

Infections and other contagious illnesses

• Human immunodeficiency virus (HIV)
• Tuberculosis

Neurological conditions

• Dementia

Weakened immune system, which may be caused by:

• Solid organ or blood stem cell transplant
• Corticosteroids, chemotherapy, or other medicines that reduce immune function
• Primary immunodeficiency

Weight

An overweight or obese body mass index (BMI) of 25 or higher is a risk factor for adults.

Don’t know your BMI? Calculate it here*

*By clicking this link, you will be redirected to a website that is neither owned nor controlled by Pfizer. Pfizer is not responsible for the content or services of this site.

Pregnancy

Your risk is increased if you are pregnant or were pregnant within the last 6 weeks. It’s not known if PAXLOVID is safe to use during pregnancy, so be sure to tell your healthcare professional if you are pregnant or have been pregnant within the last few months.

Mental Health Conditions

Mental health conditions increase your risk, including:

• Mood disorders, such as depression
• Schizophrenia spectrum disorders

Lifestyle Factors

• Doing little or no physical activity
• Current or former smoker
• Substance use disorders (such as alcohol, opioid, or cocaine use disorders)

Disabilities

Some mental, physical, and developmental disabilities increase risk, including those that:

• Limit mobility
• Reduce a person’s ability to follow preventive measures, like hand washing
• Require close contact with those who may be infected, such as a caregiver or family member
• Reduce a person’s ability to communicate their symptoms

These disabilities put you at risk:

• Attention-Deficit/Hyperactivity Disorder (ADHD)
• Autism
• Cerebral Palsy
• Charcot Foot
• Chromosomal Disorders
• Chromosome 17 and 19 Deletion
• Chromosome 18q Deletion
• Cognitive Impairment
• Congenital Hydrocephalus
• Congenital Malformations
• Deafness/Hearing Loss
• Disability Indicated by Barthel Index
• Down Syndrome
• Fahr’s Syndrome
• Fragile X Syndrome
• Gaucher Disease
• Hand and Foot Disorders
• Learning disabilities
• Leber’s Hereditary Optic Neuropathy (LHON) or Autosomal Dominant Optic Atrophy (ADOA)
• Leigh Syndrome
• Limitations with self-care or activities of daily living
• Maternal Inherited Diabetes and Deafness (MIDD)
• Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) and Risk Markers
• Mobility Disability
• Movement Disorders
• Multiple Disability (referred to in research papers as “bedridden disability”)
• Multisystem Disease
• Myoclonic Epilepsy with Ragged Red Fibers (MERRF)
• Myotonic Dystrophy
• Neurodevelopmental Disorders
• Neuromuscular Disorders
• Neuromyelitis Optica Spectrum Disorder (NMOSD)
• Neuropathy, Ataxia, and Retinitis Pigmentosa (NARP)
• Perinatal Spastic Hemiparesis
• Primary Mitochondrial Myopathy (PMM)
• Progressive Supranuclear Palsy
• Senior-Løken Syndrome
• Severe and complex disability (referred to in research papers as “polyhandicap disability”)
• Spina Bifida and Other Nervous System Anomalies
• Spinal Cord Injury
• Tourette Syndrome
• Traumatic Brain Injury
• Visual Impairment/Blindness
• Wheelchair Use