Talk to your healthcare provider about these important considerations before taking PAXLOVID

Key Safety Topics to Discuss

Medications That Cannot Be Taken With PAXLOVID

• Taking certain medicines with PAXLOVID can cause severe or life-threatening side effects or death
• It is very important to tell your healthcare professional about all of the medicines you are taking because additional laboratory tests or changes in the dose of your other medicines may be necessary during treatment with PAXLOVID
• Your healthcare professional may also tell you about specific symptoms to watch out for that may indicate that you need to stop or decrease the dose of some of your other medicines
• The table below is not a complete list of all medicines that cannot be taken with PAXLOVID. PAXLOVID may increase or decrease the levels of other medicines

Possible Side Effects

PAXLOVID may cause side effects, some of which may be serious, such as allergic reactions or liver problems. The list below doesn't include all of the possible side effects of PAXLOVID. For more information, ask your healthcare professional or pharmacist.

Some side effects of PAXLOVID are:

Allergic Reactions

Stop taking PAXLOVID and call your healthcare professional right away if you get any of the following symptoms of an allergic reaction:

• Hives, skin rash, blisters, or peeling skin
• Painful sores or ulcers in the mouth, nose, throat, or genital area
• Trouble swallowing or breathing
• Swelling of the mouth, lips, tongue, or face
• Throat tightness
• Hoarseness of voice

Liver Problems

Tell your healthcare professional right away if you have any of these signs and symptoms of liver problems:

• Loss of appetite
• Yellowing of your skin and the whites of your eyes (jaundice)
• Dark-colored urine
• Pale-colored stools
• Itchy skin
• Stomach-area (abdominal) pain

Most Common Side Effects

• Altered sense of taste (such as metallic, bitter taste)
• Diarrhea

Other Possible Side Effects

• Headache
• Vomiting
• Stomach-area (abdominal) pain
• Nausea
• High blood pressure
• Feeling generally unwell